Guide for Lung Cancer Gene Tests Published

Posted by Samantha Powell on April 8th, 2013 |

Guide for Lung Cancer Gene Tests Published

By Charles Bankhead, Staff Writer, MedPage Today

Published: April 05, 2013

Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner

All patients with advanced lung adenocarcinoma should undergo testing for EGFR and ALK mutations to determine their eligibility for targeted therapies, according to a jointly developed guideline from three organizations.

Patients should undergo EGFR testing at diagnosis of advanced disease or at recurrence or progression if they were not tested at earlier disease stages. ALK rearrangement testing is suggested by the International Association for the Study of Lung Cancer, the College of American Pathologists, and the Association for Molecular Pathology.

Patients should not be excluded from testing because of smoking status or clinical characteristics, the guideline authors said in an article published online in the Journal of Thoracic Oncology.

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