Posts in the “Clinical Trials Clinical Trials” category:

A Lung Cancer Trial Success Story

Posted by Samantha Powell on April 22nd, 2014 |

News Headline: A Lung Cancer Trial Success Story Date: 4/22/14 Outlet Full Name: About.com Author: Lynne Eldridge http://lungcancer.about.com/b/2014/04/22/a-lung-cancer-clinical-trial-success-story.htm I’ve often written about the pro’s and con’s of clinical trials. On the positive side, the only way we make progress in treating cancer is through evaluating medications and other treatments in clinical trials. On the other […]

Phase III Immunotherapy Lung Cancer Trial Stopped Early

Posted by Samantha Powell on April 18th, 2014 |

Date: 4/18/14 Outlet Full Name: Cancer Network Author: Dave Levitan http://www.cancernetwork.com/lung-cancer/phase-iii-immunotherapy-lung-cancer-trial-stopped-early GlaxoSmithKline has stopped a phase III trial of a novel lung cancer immunotherapeutic agent, after determining that it may not be possible to identify which genetic subgroups may benefit from the treatment. Vincent Brichard, the senior vice-president and head of immunotherapeutics at the company […]

New Kind of Trial Aims to Speed Cancer Drug Development

Posted by Samantha Powell on April 16th, 2014 |

Date: 4/16/14 Outlet Full Name: Reuters Author: Ben Hirschler http://www.reuters.com/article/2014/04/16/us-cancer-trials-idUSBREA3F22520140416 Scientists and drugmakers are pioneering a new kind of clinical trial that changes the way cancer drugs are studied, potentially cutting both the time and cost of bringing them to market. Instead of testing one drug at a time, a novel lung cancer study announced […]

GlaxoSmithKline Throws in Towel on Lung Cancer Vaccine Trial

Posted by Samantha Powell on April 2nd, 2014 |

Date: 4/2/14 Outlet Full Name: Reuters Author: Ben Hirschler http://www.reuters.com/article/2014/04/02/us-gsk-cancer-idUSBREA310E420140402 GlaxoSmithKline Plc (GSK) has stopped a high-profile clinical trial using a novel vaccine to fight lung cancer after deciding it will not be possible to find a sub-group of patients who might benefit. The decision comes less than two weeks after GSK said the MAGE-A3 […]

Novartis Says Lung Cancer Patients Respond to Drug in Study

Posted by Samantha Powell on March 27th, 2014 |

Date: 3/27/14 Outlet Full Name: Reuters Author: Katharina Bart http://www.reuters.com/article/2014/03/27/us-novartis-ldk-idUSBREA2Q0CN20140327 Novartis said late on Wednesday that a majority of patients given a development drug against non-small cell lung cancer had responded to the treatment, according to study results published in the New England Journal of Medicine. The Basel-based drugmaker’s LDK378 has been declared a “breakthrough […]

Pfizer’s Xalkori Shines as First-Line Lung Cancer Therapy

Posted by Samantha Powell on March 26th, 2014 |

Date: 3/26/14 Outlet Full Name: Pharma Times Author: Kevin Grogan http://www.pharmatimes.com/article/14-03-26/Pfizer_s_Xalkori_shines_as_first-line_lung_cancer_therapy.aspx Pfizer has reported positive late-stage data on a trial of Xalkori compared to chemotherapy in previously-untreated lung cancer patients with a specific gene mutation. The Phase III study of Xalkori (crizotinib) met its primary objective of significantly prolonging progression-free survival in previously-untreated patients with […]

Ariad Begins Trial of Lung Cancer Drug, Says Side Effects Will Be Different From Iclusig

Posted by Samantha Powell on March 24th, 2014 |

Date: 3/24/14 Outlet Full Name: Boston Business Journal Author: Don Seiffert http://www.bizjournals.com/boston/blog/bioflash/2014/03/ariad-begins-trial-of-lung-cancer-drug-says-side.html?page=all Ariad Pharmaceuticals has begun a trial to study a treatment for the most common form of lung cancer, and while the drug works the same way as the biotech firm’s first approved drug, Iclusig, the company doesn’t expect it to show similar side […]

ASCO: ‘Smaller, smarter’ cancer trials will yield more meaningful results

Posted by Samantha Powell on March 24th, 2014 |

Date: 3/24/14 Outlet Full Name: Healio Hematology/Oncology Author: Ellis LM http://www.healio.com/hematology-oncology/practice-management/news/online/%7Bdbf305e6-0b11-48aa-a214-f47c9874b716%7D/asco-smaller-smarter-cancer-trials-will-yield-more-meaningful-results ASCO recently released new recommendations designed to increase the likelihood of “clinical meaningful outcomes” in trials for advanced pancreatic, lung, breast and colon cancers. The recommendations — developed by the ASCO Cancer Research Committee in conjunction with other experts and patient advocates, and published […]

Glaxo’s Immunotherapy Fails to Help Lung Cancer Patients

Posted by Samantha Powell on March 20th, 2014 |

Date: 3/20/14 Outlet Full Name: Bloomberg News Author: Allison Connolly, Makiko Kitamura http://www.bloomberg.com/news/2014-03-20/glaxo-s-cancer-medicine-fails-to-meet-goal-of-trial.html An experimental GlaxoSmithKline Plc (GSK) product didn’t work in a lung cancer study, the second time the medicine failed an advanced test against cancer. The therapy known as MAGE-A3 didn’t help patients with non-small cell lung cancer live longer without the disease […]

UC Davis Researchers Have Found Potential Lung Cancer Vaccine Shows Renewed Promise

Posted by Samantha Powell on March 20th, 2014 |

Date: 3/20/14 Outlet Full Name: PR Web Author: No author http://www.prweb.com/releases/2014/03/prweb11690301.htm Researchers at UC Davis have found that the investigational cancer vaccine tecemotide, when administered with the chemotherapeutic cisplatin, boosted immune response and reduced the number of tumors in mice with lung cancer. The study also found that radiation treatments did not significantly impair the […]