The Bonnie J. Addario Lung Cancer Foundation (ALCF), in collaboration with the Van Auken Private Foundation (VAPF) is pleased to announce its first Young Innovators Team Award to support novel, innovative, transdisciplinary and translational team research with potential of high clinical impact in lung cancer. The objective of this new ALCF funding mechanism is to identify brilliant, young “out of the box” thinkers/researchers who can collaboratively deliver a meaningful and measurable result that helps ALCF move towards our goal of making lung cancer a chronically managed disease by the year 2023.
About the 2014 Young Innovators Team Awards
- The focal key words of this funding mechanism are:
- Out-of-the-box – high-risk, high-impact research that will typically not be selected for federal funding, is creative and has potential for near-term benefit to lung cancer researchers
- Collaborative – research that fosters collaboration among young researchers who haven’t worked together in the past, preferably across-institutions
- Translational – research with outcomes that can be quickly moved from the lab to the clinic, or from the bench to bedside
- Multi-Disciplinary – projects that involve multiple academic disciplines/specializations in their approach to solve a problem in the field of lung cancer
- Each selected team will comprise of at least 2 young innovators that propose to conduct first in field, innovative, transdisciplinary and transformative treatment sciences research with a high probability of near-term benefit to lung cancer patients.
- Young Innovators will be guided by mentors at their institutions, but will be the chief investigators actually driving the research project.
The idea is to encourage out-of-the-box thinking
and foster leadership skills among young innovators, instilling
confidence in them to drive breakthrough, transdisciplinary science
under a collaborative, cross-institutional paradigm.
- Progress of each research project will be reviewed and decisions on continued funding will be made by ALCF leadership and the Young Innovator Team Scientific Review Committee comprised of: David Carbone, MD, PhD (The Ohio State University), David Gandara, MD (University of California, Davis), Roy Herbst, MD, PhD (Yale School of Medicine), Giorgio Scagliotti, MD, PhD (University of Torino). Additional members may be added to the committee based on the technical area of expertise of the selected teams, and the focus of the proposed research.
- The Young Innovator Team Award will provide up to a total of $500,000 per team over a duration of 2-3 years, depending on the proposal and final decision by the Scientific Review Committee.
- The award will cover direct research costs only.
- Up to three teams will be funded.
Lung cancer patient-oriented research in the following topic areas is preferred (however, all submissions will be evaluated). Patient-oriented research: Research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator directly interacts with human subjects. This area of research includes:
- Studies of mechanisms of lung cancer initiation, progression and metastases.
- Development of new technologies for the detection, treatment and prevention of lung cancer.
- Diagnostic and therapeutic interventions, preferably new diagnostics and treatments for metastatic lung cancer especially those targeting currently ‘undruggable’ mutations against which there is no available targeted therapy.
- Early detection of lung cancer, especially via non-invasive tools.
- Identification of mechanisms of resistance to current lung cancer modalities.
- Translational research in metabolism and nutrition.
May 19, 2014 – RFA Announcement
June 3, 2014 – Online Application Submission Portal Opens
August 1, 2014 – Application Submission Deadline
August 30, 2014 – Peer Review Deadline
September 10, 2014 – Top 5 teams present to the Scientific Review Committee, in-person review
September 30, 2014 – Award Announcements and Notification