Posts in the “Clinical Trials Clinical Trials” category:

New research outlines promising therapies for small cell lung cancer

Posted by Samantha Powell on October 7th, 2014 |

Two recently published studies by a research team at University Hospitals (UH) Case Medical Center Seidman Cancer Center have the potential to advance treatments for small cell lung cell cancer (SCLC). This aggressive form of lung cancer has seen no treatment advances in 30 years and “is a disease in urgent need of new drug… Read More

Many patients excluded from clinical trials due to prior cancer, UTSW study finds

Posted by Samantha Powell on September 26th, 2014 |

Lung cancer clinical trials exclude a substantial proportion of patients due to a history of prior cancer, as shown in an analysis by cancer researchers at UT Southwestern Medical Center. Among more than 50 lung cancer clinical trials examined, more than 80 percent excluded patients with prior cancer from participating, according to the study published… Read More

Ellen Sigal and Jeff Allen Named September LUNGevity Heroes for Lung-MAP Creation

Posted by Samantha Powell on September 23rd, 2014 |

The LUNGevity Foundation has announced that Ellen Sigal, Friends of Cancer Research Chairperson and Founder, and Executive Director Jeff Allen, PhD, were recently distinguished as the September LUNGevity Heroes for the work they have done advocating for policies to improve health outcomes and cancer care, and for being responsible for the creation of groundbreaking initiatives… Read More

Yale study sees benefits of traditional lung cancer surgery

Posted by Samantha Powell on September 17th, 2014 |

Traditional surgery appears to save lives better than radiosurgery, even though it’s more invasive, when treating early-stage non-small cell lung cancer, according to Yale University. A study of 1,078 lung cancer patients’ Medicare billing records showed this to be true even considering the risks of regular surgery. “What was dramatic to me was the relatively… Read More

Treatment For Lung Cancer May Depend On Your DNA

Posted by Samantha Powell on September 16th, 2014 |

The Northside Hospital Cancer Institute (NHCI), Atlanta, has announced it will participate in a unique National Cancer Institute clinical collaboration to treat lung cancer based on a patient’s genetic profile, becoming the first to offer the clinical trial known as Lung-MAP. The study is a multi-drug, multi-arm, biomarker-driven clinical trial for patients with advanced squamous… Read More

Online Screening for Rare Lung Cancer Mutation Opens Door to New Kind of Clinical Trial

Posted by Samantha Powell on August 22nd, 2014 |

In the previous few years, several breakthrough treatments have become available for key subtypes of lung cancer. Patients who may benefit from these treatments can be pre-identified by looking for defined genetic abnormalities in their cancer. For example, patients whose lung cancer is driven by rearrangement of the gene ALK derive significant benefit from the… Read More

NCI Launches Molecular Medicine Clinical Trials; Response Genetics Nabs Profiling Contract

Posted by Samantha Powell on August 18th, 2014 |

The National Cancer Institute said today it has launched new clinical trials that will use tumor sequencing and genetic markers to help determine whether therapies targeting genetic alterations can prevent lung cancer recurrence. Separately, Response Genetics said it has been awarded a “multi-million dollar” subcontract from Leidos Biomedical Research, a contractor for the NCI-sponsored Frederick… Read More

Ambitious Lung-MAP Trial Launched With Five Novel Drugs

Posted by Samantha Powell on August 1st, 2014 |

Five novel agents for the treatment of patients with advanced squamous cell carcinoma of the lung will be evaluated in the recently launched Lung-MAP trial, an innovative biomarker-driven study that aims to improve the drug development process while exploring therapeutic options for this challenging malignancy. Plans call for enrolling up to 5000 patients through more… Read More

Possible Advance for Some Late-Stage Lung Cancer Patients

Posted by Samantha Powell on July 8th, 2014 |

Surgical biopsy is safe for certain late-stage lung cancer patients and could improve their chances of getting treated with newer types of drugs that target cancer-related genetic mutations, a new small study reveals. In many cases, surgical biopsy is too dangerous for these patients, so less-invasive methods are used, including fine-needle aspiration and core needle… Read More

Is It Time To Ask a Disturbing Question About The Geographical Location of Cancer Clinical Trials?

Posted by Samantha Powell on June 25th, 2014 |

The genesis of this commentary is the recent publication of population-based survival outcomes associated with specific malignancies in various European countries.1 This analysis, which covered the years 1999 to 2007 revealed rather striking variation in the survival of patients with the specific cancers based on geographical location. For example, five-year survival in the United Kingdom… Read More